![]() This can influence outcome of the disease and can benefit chromate-sensitive patients. Careful selection of food with relatively low chromate concentration can bring a reduction in the total dietary intake of chromate per day, and thereby can minimize the risk for endogenous activation of immunocompetent cells in chromate-sensitive individuals. The purpose of such diet is to reduce the uptake of chromate by the body from the diet. One of the methods of treating such vesicular hand eczema is low chromate diet. It has been observed that such hand eczema improves with diet low in chromate. Such hand eczema flares up when such patients take diet high in chromate, or when orally challenged with potassium dichromate. One of the distinctive manifestations of chromate allergy is chronic, recurrent, vesicular type of hand eczema. Many times, the skin lesion may resemble nummular eczema, while some of the cases may present with atopic eczema look. The allergic reaction may confi ne to the site of contact or there may be widespread eruptions with or without flexural accentuation. The degree and pattern of chromate allergy varies from patient to patient. Once developed, chromate sensitivity tends to persist for a long time. Allergic contact dermatitis due to chromate sensitivity is not uncommon in clinical practice and the prevalence rate of chromate sensitivity is reported to be 6% according to various studies.
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